
Vicodin (generic name hydrocodone-acetaminophen) is a prescription medication containing a powerful opioid (hydrocodone) and an over-the-counter antipyretic (acetaminophen). Vicodin is a pill and is meant to be swallowed. However, like many pills, people may misuse Vicodin by crushing and either snorting or dissolving it in water and then injecting it. People do this to get the hydrocodone opioid into their bloodstream faster, which delivers a sensation of being high.
Manipulating medications this way is incredibly dangerous. Risks include infections, tissue damage, overdose, and death.
[Health Warning: Snorting Vicodin can be dangerous to your health and even life-threatening. It can lead to severe respiratory depression, coma and overdose as well as a myriad of other health problems like nasal damage.]
The prescription painkiller Vicodin contains two ingredients:
In 2014, officials classified Vicodin as a Schedule II drug, due to concerns about misuse and addiction.[5]
Vicodin is used short term to help people with mild to moderate pain that can’t be controlled with safer therapies like aspirin or ibuprofen. Vicodin along with other opioids painkillers are intended to be used on a short term basis only, such as after a surgery or a dental procedure. [1]
Vicodin and other opioids should not be used long-term as evidence shows that they have significant harms and side effects with long-term use, including:[13]
People using Vicodin in order to get high may do so in a few ways. They may take more or higher doses of Vicodin at a time than prescribed by their doctor. They may also ingest the medication in a way other than by mouth, such as crushing the pill and then either sniffing/snorting it or injecting it. [4]
Tampering with tablets by snorting or injecting them allows Vicodin to enter the bloodstream and ultimately the brain more quickly.
Users experience a more intense, rapid high via this method.
Tampering with Vicodin is dangerous, no matter whether you snort the substance or inject it. Neither is safe.
Vicodin tablets should be swallowed orally. The ingredients aren’t made to interact directly with the sensitive tissue inside your nose and throat.
Potential complications include the following:[3],[10]
Injecting Vicodin, or any medication for that matter, can lead to the following consequences:[10]
One significant danger of misusing Vicodin is severe liver toxicity and damage. This is because Vicodin contains acetaminophen, which is safe at therapeutic doses (up to 1000mg every 4-6 hours) but harmful at higher doses. Research indicates that acetaminophen can be toxic at 7.5 grams per day. [12]
And people who misuse Vicodin tend to use larger amounts than recommended and misuse it by snorting or injecting it, which puts them at risk for severe liver damage.
Acetaminophen toxicity is the leading cause of liver transplants in the U.S. and is responsible for about 56,000 emergency department visits per year.[12]
Yes. Since 1999, more than 760,000 people have died from opioid overdoses. [6] Vicodin, particularly if snorted or injected, is an opioid that can cause overdose. [7] People can overdose accidentally even if they are taking their medications orally as prescribed. However, you are even more likely to experience an overdose if you misuse your medication by snorting or injecting.
Symptoms of Vicodin overdose include the following:[8]
Anyone with these symptoms is experiencing a medical emergency. Call 911 and follow the operator’s instructions carefully. If Narcan is available, administer it immediately.
Vicodin is a Schedule II Controlled Substance, which means that it has a legitimate medical use but also has a high risk of misuse, dependence, and addiction. It also means that it is highly regulated.
Every state has different laws pertaining to illegal Vicodin possession and misuse. However, it is illegal no matter where you live in the United States.
In some states, like California, it is considered a misdemeanor punishable by up to one year in jail and/or $1,000 in fines.
However, other states, such as Georgia, have harsher laws and consider opioid possession a felony, carrying up to 30 years in jail, depending on the quantity.[11]
Unlawful Vicodin possession includes having and using it without a prescription, buying it on the street, and possessing it with intent to sell.
People who misuse Vicodin may struggle to quit without help. Their withdrawal symptoms can push them back to using, even when they want to quit.
Bicycle Health offers Suboxone treatment. This medication can reduce withdrawal symptoms and limit drug cravings. With the help of this medication, you could stop using illicit drugs and start living a different life.
The Bicycle Health team uses telemedicine to connect with patients. You’ll have safe, secure appointments from home, and you’ll pick up your medications at a pharmacy near you.
Contact us to find out if this model is right for you.

Peter Manza, PhD received his BA in Psychology and Biology from the University of Rochester and his PhD in Integrative Neuroscience at Stony Brook University. He is currently working as a research scientist in Washington, DC. His research focuses on the role of the brain dopamine system in substance use disorders and in aging. He also studies brain function in obesity and eating disorders.
Breaking Down a Peer-Reviewed Publication Describing Bicycle Health’s Opioid Use Disorder Treatment Program

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