
Heroin overdose deaths have been up and down over the past few years. Impacted by the availability of other opioid substances, heroin overdose deaths have continued to be high even in years when they experienced a small decline.
For example, in 2020, overdose deaths caused by heroin dropped 7% when compared to 2019, but 13,000 people still fell victim to the drug. This number, though lower than 2019, was still seven times higher than it was in 1999. It is estimated that about one-fifth of all overdose deaths that occur involve the use of heroin. [1]
The risks of heroin alone are bad enough. The drug can slow down and even stop the central nervous system, causing breathing to stop. But today’s heroin is mixed with even more potent substances like fentanyl, an opioid that is 50 times stronger than heroin, to make it stronger and cut costs.[2] This makes it even more deadly for long-time users as well as those who experiment with the drug, since it’s impossible to know exactly how potent any given batch will be.
There are medications that can be effective in helping people to stop taking heroin while managing the accompanying withdrawal symptoms. Contact Bicycle Health today to learn more about your options.
Heroin is a highly addictive opioid drug derived from morphine, which is a natural substance extracted from the seed pod of the opium poppy plant. Easily available on the street, heroin is known as a deadly substance due to the following characteristics:
Heroin can cause death in many ways, but the most common cause of death due to heroin use is overdose.
An overdose occurs when an individual takes a high dose of heroin, which overwhelms the body's ability to metabolize the drug. This can result in respiratory depression, which is the slowing or stopping of breathing.[4] When breathing slows down or stops completely, the body does not receive enough oxygen, leading to hypoxia (oxygen deprivation). This damages vital organs like the brain, heart, and lungs.
Heroin works by binding to opioid receptors in the brain and activating the brain's reward system, causing a rush of “feel-good” chemicals and a decrease in pain. However, when taken in large amounts, heroin can cause the body's respiratory centers to become depressed, leading to slowed breathing or respiratory arrest, which can be deadly.
Additionally, the risk of overdose is higher when heroin is mixed with other substances, such as alcohol or benzodiazepines, or when the heroin itself is mixed with other drugs like fentanyl. Since this often occurs without the user’s knowledge, it can be incredibly difficult to know the dose that will not lead to life-threatening overdose.
In addition to overdose, heroin can cause death in other ways over time. For example, infections, collapsed veins, and damage to vital organs like the heart and lungs can occur with ongoing use that can lead to deadly disorders or breakdown of the body.
Heroin use and overdose can affect anyone of any age, culture, gender, or class who uses the drug, whether they are using it only occasionally or using it multiple times per day. However, there are some populations that are at higher risk of dying from heroin use, if for no other reason than their population has high rates of using heroin. For example, non-Hispanic white men between the age of 18 and 25 year old making less than $20,000 per year and living in the northeast U.S. are more at risk.[9]
Other populations that are more at risk include the following:
It's important to note that while these populations may be at higher risk of heroin overdose, anyone who uses the drug could potentially die due to overdose.
Heroin overdose death rates are influenced by a variety of factors, including individual characteristics, environmental issues, and mental health as well as whether or not someone is on standby with the right medication to help the person survive should the worst occur.
Some of the key factors related to heroin overdose death rates include the following:
It should be noted that many people who struggle with heroin use and OUD do not fit the mold of what people think a heroin user should look like or act like based on TV and movies. One does not need to fit this description in order to have an OUD related to heroin and be at risk of overdose.
Heroin is an opioid, which means that it works by binding to opioid receptors in the brain. When the body becomes accustomed to a certain level of opioids in the body, it responds with significant withdrawal symptoms when those levels drop.
Opioid withdrawal symptoms are often a huge deterrent when it comes to getting and staying in treatment for OUD related to heroin use. The good news is that there are medications that can bind to the opioid receptors in the place of heroin and mimic its effect in the body, staving off withdrawal symptoms, and making the detox process much more comfortable.
At Bicycle Health, we can connect you with these medications and help you to get the treatment you or your loved one needs to stop using heroin and block the risk of overdose. Call now to find out more about the different medications available and discuss the right path forward for your needs. Don’t wait to get started. The right treatment can save your life.

Peter Manza, PhD received his BA in Psychology and Biology from the University of Rochester and his PhD in Integrative Neuroscience at Stony Brook University. He is currently working as a research scientist in Washington, DC. His research focuses on the role of the brain dopamine system in substance use disorders and in aging. He also studies brain function in obesity and eating disorders.
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