Injecting (or shooting) Suboxone can lead to unpleasant withdrawal symptoms, infections, blood clots and vein damage. The method also doesn’t produce the high people are looking for.
Suboxone contains buprenorphine (which stops working at high doses) and naloxone (which blocks high doses of buprenorphine). Shooting the drug is more likely to make you feel sick from precipitated withdrawal than high.
If you’re tempted to inject or misuse your Suboxone, talk to your doctor. You may need additional help for your opioid use disorder (OUD).
It’s technically possible to inject Suboxone. The medication comes in a dissolving strip or tablet. Some people apply Suboxone to liquid, wait for it to dissolve, and inject the fluid.
Shooting Suboxone is never smart. The drug isn’t designed to enter your body through your veins. Never try this method.
mild high when misusing Suboxone. But it’s very rare for anyone who has previously used any kind of opioid to get a substantial high from injecting Suboxone.
In one study, people who injected Suboxone said they felt “nothing,” including no euphoria, from the practice.[1] In a second study, people said they had a low “desire to take the drug again” after injecting dissolved Suboxone.[2]
Suboxone won’t get you high due to the naloxone component. Naloxone is an opioid antagonist, meaning that it attaches to opioid receptors in your brain, reversing and blocking the effects of other opioids.[11]
Naloxone products like Narcan are life-saving solutions during an overdose. They effectively kick stronger drugs off their receptors and cap them, stopping an overdose in minutes and restoring breathing rates.[11]
Suboxone contains a very low dose of naloxone that doesn’t do anything at a normal dose. You won’t feel it, and it won’t interfere with the buprenorphine in your dose.[10]
However, if a person injects Suboxone, both the buprenorphine and the naloxone enter the bloodstream. The naloxone “overrules” the buprenorphine, preventing the person from getting high and also preventing an accidental overdose.
Problems associated with injecting Suboxone are serious. Some can be life-threatening.
If you inject Suboxone, you will experience precipitated withdrawal, characterized by the following symptoms: [3]
People who start Suboxone too early can develop precipitated withdrawal. Typically, doctors recommend a gap of several hours between the last drug dose and your first Suboxone dose to prevent this problem.[7]
However, people who misuse Suboxone may not realize these risks and experience precipitated withdrawal. The symptoms are significant, and case studies suggest they’re sometimes bad enough to require a hospital stay.[7]
Suboxone should dissolve beneath the tongue and not enter your body through the bloodstream. Injecting the drug can lead to the following complications:[4]
Anyone who misuses drugs with a needle can develop infections. Unfortunately, the issue is common. In one study, 97% of people with infections caused by drug injection used opioids, and 80% of the infections were caused by the S. aureus bacteria.[7]
Your risk of infections from injecting Suboxone isn’t necessarily higher or lower than the risk of infection from using any other drug. Anytime you push a needle into the skin to use drugs, an infection is possible.
Researchers say buprenorphine products are six times safer than methadone products in terms of overdose risk.[5] But combining Suboxone with medications like benzodiazepines can lead to extreme sedation and overdose.[4]
Symptoms include the following: [3]
If your opioid use disorder was previously controlled on Suboxone, injecting the medication indicates you’re not fully in control. It could also lead to problematic opioid use.
Speak with your treatment provider immediately if you’re feeling compelled to inject Suboxone. There’s a chance you may need to return to a treatment program or receive additional support right now.
The prescription medication Sublocade is very similar to Suboxone. It’s an injectable medication designed for OUD. This table explains their differences:[9,10]
Sublocade doesn’t contain naloxone, so it’s not the same as Suboxone. But some people benefit from treatment consisting of only buprenorphine.
Sublocade is very hard to misuse, as the drug is administered by doctors in appointments. You aren’t given the drug to take home. Instead, you must go to the doctor to get it.
Suboxone is a very effective and safe treatment for opioid use disorder when taken as prescribed. There are several benefits of Suboxone that far outweigh the risks that come from injecting the drug.
Since buprenorphine is a partial opioid agonist, this medication does not cause the potent high that some other opioids (e.g., fentanyl) do. Instead, buprenorphine binds to opioid receptors in the brain for a full day or more, reducing withdrawal symptoms, including anxiety, intense cravings and physical discomfort.
By suppressing withdrawal symptoms and cravings, the individual taking Suboxone can focus on recovery. Often, Suboxone is taken indefinitely since it is so effective at promoting long-term recovery.
Using medications like Suboxone could help you to do the following:[6]
The majority of people who misuse Suboxone do so to treat an underlying opioid use disorder (OUD).[4] If you’ve been buying Suboxone from dealers and injecting it, there is a better and much safer way forward.
Talk to your doctor about your opioid misuse history, and ask about entering a treatment program or using Suboxone.
If you have a Suboxone prescription and you’ve misused it, talk to your doctor. You may need a stronger dose of medications to keep your OUD under control, or you may need a different recovery setting.
The more open and honest you can be with your provider, the more likely you are to safely and appropriately use your medications to get the desired results and maintain long-term abstinence.
Suboxone is a powerful prescription medication designed to help people overcome OUD. If you’re using the medication per your doctor’s instructions, you’re not misusing it. However, some symptoms suggest that your drug use is problematic.
You could need help with Suboxone misuse if these signs apply to you:[12]
Talk with your treatment team about how you’re using Suboxone. Together, you can find a solution.
Suboxone is a prescription medication proven to help people overcome OUD. If you’re injecting drugs, or considering doing so, it’s time to consider treatment. With help, you could stop withdrawal symptoms and cravings, allowing you to build a healthier life in sobriety.
Bicycle Health offers online treatment options for people just like you. Find out how our process works and see if it’s right for you.
Peter Manza, PhD received his BA in Psychology and Biology from the University of Rochester and his PhD in Integrative Neuroscience at Stony Brook University. He is currently working as a research scientist in Washington, DC. His research focuses on the role of the brain dopamine system in substance use disorders and in aging. He also studies brain function in obesity and eating disorders.
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